Max’s paper on how Afadin suppresses ILC metastasis is out in the JOURNAL OF PATHOLOGY. We show that Afadin stabilizes the E-cadherin to F-actin link through the  α-catenin binding CC domain.

Peter identified prognostic signatures based on collective invasive HNSCC tumoroids in Collagen  Published in ONCOGENE. A wonderful collaboration with Stefan Prekovic and his lab members next door.

Peter’s first paper is out in ORAL ONCOLOGY REPORTS. Here we show that a keratin-based invasion signature of HNSCC organoids is prognostic in clinical cohorts. Invasion architecture and keratin profiles matter!