Max’s paper on how Afadin suppresses ILC metastasis is out in the JOURNAL OF PATHOLOGY. We show that Afadin stabilizes the E-cadherin to F-actin link through the  α-catenin binding CC domain.

After an initial quick conception it took a while, but here it is! Collective breast cancer invasion hinges on YAP-centered mechanotransduction cues. Published in NATURE COMMS. A team effort with the De Rooij and Khalil labs.

Peter’s first paper is out in ORAL ONCOLOGY REPORTS. Here we show that a keratin-based invasion signature of HNSCC organoids is prognostic in clinical cohorts. Invasion architecture and keratin profiles matter!