Cell Adhesion
and
Cancer Progression
Themes in the Lab
Latest News
A PATHOLOGY SOP TO CORRECTLY DIAGNOSE ILC
The ELBCC Pathology working group published a landmark paper in MODERN PATHOLOGY to correctly diagnose lobular vs ductal breast (NST) cancers. Check out the ELBCC website for a pdf version of the paper and the SOP.
INVASIVE RNA SIGNATURES ARE PROGNOSTIC IN HNSCC
Peter identified prognostic signatures based on collective invasive HNSCC tumoroids in Collagen Published in ONCOGENE. A wonderful collaboration with Stefan Prekovic and his lab members next door.
YAP-BASED COLLECTIVE INVASION IN BREAST CANCER
After an initial quick conception it took a while, but here it is! Collective breast cancer invasion hinges on YAP-centered mechanotransduction cues. Published in NATURE COMMS. A team effort with the De Rooij and Khalil labs.
A PROGNOSTIC INVASION SIGNATURE FOR HNSCC
Peter’s first paper is out in ORAL ONCOLOGY REPORTS. Here we show that a keratin-based invasion signature of HNSCC organoids is prognostic in clinical cohorts. Invasion architecture and keratin profiles matter!
FLEXIBLE ILC CELLS ADAPT TO THE COLON MICROENVIRONMENT
Our team co-authors on this wonderful work published in J PATHOL where Gronewold et al. demonstrate restoration of junctional characteristics in metastatic ILC cells to the colon. Stromal signals at work??
Videos on YouTube
The ELBCC had its own designated YouTube Channel. Here you can find videos containing footage from the European Editions of the 2022 and 2024 ILC Symposia.
MECHANOCONTROL
A promotional video from the MechanoControl Consortium
ILC AWARENESS VIDEO
An ILC infomercial from a Rian, Sabine and Patrick
DYNAMI LECTURE 2024
The 2024 Leigh Pate Memorial Dynami Lecture by Patrick